SINGLE-CELL ANALYSIS REVEALS THE CELLULAR AND MOLECULAR CHANGES OF LIVER INJURY AND FIBROSIS IN MICE DURING THE PROGRESSION OF SCHISTOSOMA JAPONICUM INFECTION

Single-Cell Analysis Reveals the Cellular and Molecular Changes of Liver Injury and Fibrosis in Mice During the Progression of Schistosoma japonicum Infection

Schistosomiasis is a parasitic disease that poses a serious threat Skin Cream to human health.However, the pathogenic mechanism during the progression of Schistosoma japonicum infection remains unclear.In order to elucidate this mechanism, we used single-cell RNA sequencing (scRNA-seq) to investigate the transcriptome characteristics of the cellula

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Land Snail Sphyradium doliolum (Stylommatophora Orculidae) in Ukraine and Moldova: Distribution, Habitats, Variability and Origin

All existing data and most of the available materials on Sphyradium doliolum from Ukraine and Moldova are reviewed.The species is reported from 38 localities (some including several sites) on uplands east of the Carpathians, the Dnipro Upland and in the Crimean Mountains.It mostly inhabits the broadleaved forests, but in one locality was found in a

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The Landscape of Novel Therapeutics and Challenges in Glioblastoma Multiforme: Contemporary State and Future Directions

Background: Glioblastoma multiforme is a malignant intracranial neoplasm that constitutes a therapeutic challenge because of the associated high morbidity and mortality given the lack of effective approved medication and aggressive nature of the tumor.However, there has been extensive research recently to address the reasons implicated in the resis

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